The ball Pele scored his 1,000th goal with is one of around 2,000 pieces of memorabilia from his glittering career to be sold at Julien's Auctions.
It's expected to sell for around $40,000-60,000 in the June 7-9 sale in Los Angeles.
He achieved the feat at the Maracana Stadium in Rio de Janeiro on November 19, 1969, playing for Santos FC against Vasco de Gama.
Pele is often described as the greatest football player of all time, having scored a world record 1,283 goals over the course of his career.
He began his career in 1956, utterly dominating the Brazillian leagues from the outset. He achieved international fame in 1958, when he became the youngest player ever to play in the world cup (he was just 17).
The sale will include a copy of the Jules Rimet Trophy, a number of winner's medals and a huge range of game worn shirts, boots and other artefacts.
Pele comments: "Having donated a significant portion of my collection to the City of Santos, I have decided to allow fans and collectors to own a piece of my history as well.
"I hope they treasure these artifacts and share my story with their children and generations to come.
"I will also be donating a portion of the proceeds from the auction to Pequeno Principe, the largest pediatric hospital in Brazil."
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