The gold winner's medal awarded to Uruguayan winger Jose Andrade in the inaugural FIFA World Cup in 1930 could make £30,000-40,000 ($42,387-56,516) in London on April 26.
It will be one of the star lots of a sale of football memorabilia at Graham Budd Auctions.
Uruguay were the winners of the first ever FIFA World Cup
It's inscribed: "COUPE DU MONDE, MONTEVIDEO, JUILLET, 1930, JOSE LEANDRO ANDRADE".
The event was held in Uruguay, with the home team the favourite to win - a feat they pulled off with ease.
Thirteen teams competed, with the majority coming from South America.
This was largely due to the relative difficulty and expense of international travel at the time.
Andrade was nicknamed Maravilla Negra (the Black Marvel) and was regarded as one of the best players of his era.
Despite being past his prime, he still excelled as one of the best Uruguayan players in the tournament.
Sadly his life fell apart after retirement and he died in poverty in 1957, following years of alcoholism.
The shirt midfielder John Anderson wore for Manchester United in the 1948 FA Cup Final is offered with an estimate of £15,000-20,000 ($21,193-28,258).
United beat Blackpool 4-2 in the game, with Anderson scoring in the 82nd minute.
We have a wealth of football memorabilia for sale, including this menu signed by the entire 1966 England World Cup squad.
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