A piano John Lennon played on the Beatles' Sgt Pepper's Lonely Hearts Club Band album is expected to make $1.2m-1.8m at Sotheby's.
The lot will be one of the highlights of Sotheby's A Rock and Roll Anthology: From Folk to Fury auction in New York on December 10.
Lennon also wrote A Day in the Life and numerous other songs at the John Broadwood & Sons custom piano, which stood in the music room at Kenwood - his home in Weybridge, Surrey.
It's also one of three pianos on which the band plays the 40 second long E Major chord on A Day in the Life, which closes the album.
In 2000, the piano Lennon used to write Imagine sold for £1.4m ($2.1m), a sum the present lot could easily surpass.
Another highlight of the sale is the original autograph draft for the Eagles' love it or hate it anthem Hotel California.
It's expected to make $500,000-700,000.
The song was one of the biggest hits of the 1970s and its gnomic lyrics have been endlessly interpreted.
The band themselves have explained that it's based on their disillusionment with the party lifestyle of California in the mid-70s.
If it hits its high estimate, the lot will become one of the most valuable sets of original rock lyrics ever sold.
We have an extraordinary piece of Lennon memorabilia for sale.
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