Two pages from Mozart's Serenade in D major will carry a $120,000-180,000 estimate to Swann Auction Galleries' November 26 sale in San Francisco.
Written in Vienna in July and August of 1773, when the composer was just 17, the work is scored for two oboes/flutes, two horns, two trumpets and a solo violin.
The working draft comprises bars 52-70 of the score and features annotations in brown ink.
It was initially bound in a volume titled Cranz Music Volume 1 by Leopold Mozart, the composer's father; although over the years various leaves from the volume were sold or otherwise dispersed.
The record for a score by Mozart was set in 2007, when two pages of the Sinfonia Concertante in E realised £110,900 ($228,484) at Sotheby's London.
We have a piece of a score by legendary saxophonist John Coltrane, featuring handwritten notations.
A lot comprising five handwritten letters by Albert Einstein to fellow physicist Paul Hertz is valued at $70,000-100,000.
The letters were penned between 1910 and 1915, and reference problems arising in the development of his theory of relativity - which was first published in 1916.
A bible inscribed by Einstein realised $68,500 at Bonhams New York in June of this year.
A letter by Robert E Lee written in 1855, six years before he became leader of the North Virginian confederate army, will also feature at the auction, with an estimate of $25,000-35,000.
In 2007, a copy of Lee's terms of surrender to Ulysses S Grant realised $537,750 at Heritage Auctions.
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