A space flown page of the Apollo 11 flight plan is coming to auction at Heritage next month.

The single page, annotated by Neil Armstrong during the historic mission, is expected to be the highlight of the Space Exploration Signature Auction, which runs from October 14 to November 2.

This page of the flight plan from Armstrong’s first steps on the Moon sold for $152,000 in 2010

It once formed part of the personal collection of Buzz Aldrin, and comes complete with the second man on the Moon's own letter of authenticity.

"It is part of the entire document that was carried to the Moon in Command Module Columbia during the first lunar landing mission," Aldrin writes.

"This sheet is from the detailed timeline section and covers hour nine to the beginning of eleven in the mission."

Apollo 11 flight plan pages have proved themselves strong performers in the past. The page detailing the preparations for Armstrong's first step onto the Moon auctioned for $152,000 at Bonhams in 2010, while a star chart from the flight plan realised $12,200 in the same year.

No estimate has yet been provided for the item, yet we believe its huge appeal, and the addition of Armstrong's notes, should see it achieve in the region of $20,000.

"The flight plan was probably the single most important document related to the success of our mission," adds Aldrin.

"It provided a time schedule of crew activities and spacecraft maneuvers to accomplish the first lunar landing."

The recent death of Armstrong has seen his signature rise considerably in value, with signed photos having climbed by 26.05% between 2011 and 2012, according to the PFC40 Autograph Index.

We have two Neil Armstrong autographs in a single autograph book currently available in our auction, which runs until Thursday (September 27).

We will bring you further details from Heritage's auction over the coming weeks.