A 1935 Delahaye 135 S is valued at $1.4m-1.9m ahead of RM Auctions' Paris sale on February 3-4.
The car has passed through the hands of some of the most prestigious French collectors over the course of its life, including those of Jean-Philippe Peugeot, of the Peugeot Motor Company.
Later it came into the possession of Jean Sage, director of Renault's F1 team during late 1970s and early 1980s.
The house commented: "For decades, chassis 46094 has been a familiar sight on the international classic car scene, competing in many of the world's leading historic races and retrospectives driven by its famous former owner, Jean Sage.
"Suitable for road or track, it is a versatile entry into almost every significant event around the world and would be highly prized in any collection."
The 135 S marked a shift in Delahaye's production. It was the first dedicated sports car the company ever produced and it performed well in events across Europe.
This model achieved second place at Le Mans in 1937 and victory at the Grand Prix des Frontières during the 1940s.
RM Auctions' Arizona sale will showcase more contemporary cars, including a Ferrari Classiche-certified 1990 F40.
Please sign up to our free newsletter to receive exciting news about classic car auctions.