A first edition copy of Karl Marx's Das Kapital signed by the author is valued at £80,000-120,000 ($117,110-175,665).
The lot will cross the block at Bonhams London on June 15.
It's inscribed to Johann Georg Eccarius, chairman of the worker's union First International - a man Marx described as "one of my oldest friends and adherents".
The signature dates to 1867.
The pair had a spectacular falling out in the 1870s, after Eccarius appeared to claim credit for some of Marx's ideas in the Telegraph newspaper.
Bonhams explains: "Very few presentation copies of the first edition are known to have survived, but at least two others were inscribed by Marx on the same day in London, presumably when the first batch arrived from Hamburg."
One of these other signed copies, inscribed to a Professor Edward Spencer Beesly, made £115,000 ($168,345) at Dreweatts & Bloomsbury in 2010.
A handwritten manuscript from 17th century scientist Sir Isaac Newton is expected to make £50,000-70,000 ($73,193-102,471).
It's titled: "The question stated about abstaining from blood" and grapples with the morality of eating blood, using the Old Testament as its source.
It appears in his work The Chronology of Ancient Kingdoms (published posthumously in 1728).
He concludes that it is still wrong to eat blood.
Newton apparently avoided black pudding for this reason. Rabbits were also off the menu as they were usually dispatched by strangulation, meaning the meat stayed bloody.
Please sign up to our free newsletter to receive exciting news about book and manuscript auctions.