A piece of original Superman art by renowned fantasy artist Frank Frazetta is expected to sell for around $10,000-20,000 at Hake's.
The lot will star in an online sale that closes on November 12.
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The painting dates to 1988 and was executed in the style of the Man of Steel's original creators, Jerry Siegel and Joel Schuster.
Hake's president Alex Winter explained: "This was the only depiction of Superman Frank Frazetta ever created. It was a commissioned job to commemorate the character's 50th anniversary."
The lot was formerly housed in artist Kevin Eastman's Words and Pictures Museum in Massachusetts.
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