The auction is taking place at the Liverpool Institute for the Performing Arts and the seven-inch record is signed by every one of the Fab Four: Lennon, McCartney, George Harrison and Ringo.
Memorabilia items signed by all four members of the Beatles are always highly coveted, such as this in-flight magazine which is for sale elsewhere on the markets.
In this case, the very rare copy of the record is estimated at £7,000 to £8,000 (up to $13,200) - which seems a little modest and we reckon it is likely to go for more.
There are a number of other quite interesting items in the sale, too. In particular, a cap belonging to John Lennon is expected to bring up to £4,000 - a coincidence as his cowboy hat recently sold.
There's even a piece of the Cavern Club stage which is estimated to reach up to £1,800.
Beatles watchers will be aware that The Fame Bureau auction is taking place today, and some highly appealing pieces of Beatles memorabilia are going under the hammer as we speak.
This includes four black and white ceramic tiles reading "A, B, E and Y from the Abbey Road sign pictured on the back cover of the Beatles album of the same name.
Watch this space for the results of that sale.
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