Pissarro's Le Jardin de Maubuisson will star at Bonhams' Impressionist and Modern Art auction on November 5 in New York with a $2m high estimate.
Dating from 1882, the highly evocative work details Pissarro's neighbour working her plot in the market gardens behind his home in Pointoise, and shows the artist at the height of his abilities.
The only painter to exhibit at all eight impressionist exhibitions between 1874 and 1876, Pissarro was revered by his contemporaries, including Monet and Van Gogh, and was described by Cezanne as "a man worth consulting and something like God himself."
His reputation among collectors is growing year on year. A collection of four paintings by the artist sold at Christie's New York for $14.6m in February 2008, smashing the previous Pissarro record of $9m set in 2004 by the same collection - achieving an increase in value of 62%.
Guy Bennett, head of impressionist and modern art at Christie's New York, told Blouin ArtInfo in 2009: "Pissarro's market is incredibly undervalued. On the whole, the artist's price range at auction is between $1 million and $4 million, which is remarkable, considering where some of our other artists are selling and how influential Pissarro was. Our clients have realized that, and that's why you've seen this increase in his price point."
The auction will preview in New York from November 1-5.