Highlights include an oil painting by Henry Scott of the American clipper Glory of the Seas, which is estimated to net £20,000-30,000.
Glory of the Seas was the last in a long line of medium clippers designed and built by the great Donald McKay at his east Boston yard.
Launched in October 1869, the figurehead of the ship is preserved at the India House, New York. The work was previously hung in London's Fortnum and Mason.
A portrait of Frederic, Lord Leighton by John Hanson Walker, estimated at £10,000-15,000, is also expected to generate plenty of interest.
After its exhibition at the Royal Academy in 1877, the Art Journal commented: "The portrait which we most affect in Gallery IV is that of F Leighton in a brown velvet jacket. We are glad to see that the artist, J Hanson Walker, has really risen to the height of the subject."
A £12,000-valued scene of ruins by a follower of Giovanni Paolo Panini evokes the classical architectural landscapes of Italy, while a landscape of Port Bannatyne, Isle of Bute by William Davis and a portrait of Lady Jane Dance by Sir James Jebusa Shannon could both surpass £4,000.
Veronique Scorer, head of Bonhams' Knightsbridge pictures department, comments: "The auction offers a fantastic opportunity to acquire an interesting and decorative painting from a range of periods."