Bedroom, Strandgade 30 (1906) by Vilhelm Hammershoi (1864-1916) was the top lot of an auction of 19th century European and Orientalist art at Christie's London on November 26.
The painting realised £698,500 ($1.1m), an increase of 99% on a £350,000 ($400,250) high estimate.
The painting depicts a corner of the artist's bedroom at his home in Copenhagen, and displays a masterly command of light and composition.
Hammershoi's mysterious, melancholic works often project a sense of unease and dissonance.
He was critically acclaimed within his lifetime, and in recent years has been the subject of two high profile retrospectives - at the Musee d'Orsay in France and the Guggenheim in New York.
His record was set in 2012, when Ida Reading a Letter realised £1.7m ($2.7m) at Sotheby's in London.
Alfred De Dreux's Guerrier Ottoman A Cheval made £458,500 ($740,478), towards the higher end of its £300,000-500,000 ($480,300-800,500) estimate.
One of just a handful of Orientalist paintings by De Dreux (1810-1860), it depicts a mounted Ottoman soldier firing a pistol.
Best known for his equestrian paintings, De Dreux achieved phenomenal success in his lifetime - receiving commissions to paint the horses of aristocratic families across Europe, and becoming a favoured artist of both King Louis Phillipe and his successor, Napoleon III.
African Groom Holding a Stallion, with a Dog achieved his highest price at auction, selling for £848,000 ($1.6m) at Christie's London in 2006.
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