Gioacchino Assereto's Ecce Homo will lead an auction of old master and British paintings at Sotheby's London.
The work carries an estimate of £100,000-150,000 ($154,240-231,360) ahead of the December 10 sale.
Assereto (1600-1649) was a baroque-era painter whose work is well regarded among collectors.
"Ecce Homo" means "behold the man" and was the phrase spoken by Pontius Pilate when he showed Christ off to the crowd prior to the crucifixion.
It has been a popular theme for artists across the centuries.
Sotheby's comments: "This is Assereto's last known version of the subject and can therefore be seen as the culmination of his treatment of it.
"The dynamic composition and free brushwork, along with the reduced palette, led Zennaro to date the painting to the 1640s."
Pieter Brueghel the Younger's A Village Street is valued at £80,000-120,000 ($119,515-179,272).
The painting depicts a Flemish village and dates to the 1630s, towards the end of Brueghel's life. It's one of a series of works focusing on peasant villages.
Sotheby's comments: "These late landscapes seem to have been quite personal in character, for each scene is known in only a few versions, and all are free of the prolific repetition that characterised much of his studio's output.
"No other versions of this particular composition are known."
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