Keith Haring's Andy Mouse (1986) led a sale of prints and multiples at Christie's New York on April 23-24.
It realised $629,000, an increase of 57.2% on a $400,000 estimate.
The print depicts Andy Warhol as a mouse surrounded by dollar symbols, a reference to Warhol's twin obsessions of fame and branding - both Haring and Warhol were devotees of Disney and Mickey Mouse.
Haring explained in an interview: "You see, whatever I've done would not have been possible without Andy. Had Andy not broken the concept of what art is supposed to be, I just wouldn't have been able to exist."
The lot exceeded the $600,000 paid for another Andy Mouse work in 2010.
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